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Wilson lab


elucidating the mechanisms that underlie the development of the vertebrate forebrain and eyes

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Wilson lab


elucidating the mechanisms that underlie the development of the vertebrate forebrain and eyes

About the Wilson lab

The primary aim of our research group is to elucidate the mechanisms that underlie the development of the vertebrate forebrain and eyes. 

We study the processes by which cells and tissues take shape, the signaling pathways that control cell migration and allocation of cell identity, the formation of neural circuits and the development of behavior. For our studies, we work with zebrafish, as the brains of fish embryos are relatively simple and are amenable to genetic, molecular and imaging approaches.

Here you can read about our research, and find links to our publications. If you don't have a background in science, we have written publication summaries that will tell you about the outcome of our research.
 


Wilson lab outreach

We are currently accepting applications for the A-level work experience programme. Click here for more information about the A-level work experience programme and for details of how to apply in 2018.

For information about other Zebrafish UCL outreach programmes, click here.

 

News

Follow us on twitter @stevewilsonlab

 
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Research Projects


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Images


Images


WILSON LAB Images

Select a circle above for Wilson lab images, movies and fun images. For media from across the Zebrafish UCL labs, go to the Zebrafish UCL images section.

Many of our images are available for download from Wellcome Images. Simply search the collection for 'Zebrafish'.

 
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Publications


Publications


Publications

To read summaries of our publications that need less scientific background to understand than the original paper click here.  

For a full list of Wilson lab publications by year, click here. 

 

Recent publications

Roussigné M, Wei L, Tsingos E, Kuchling F, Alkobtawi M, Tsalavouta M, Wittbrodt J, Carl M, Blader P, Wilson SW. (2018)
Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells.
Proc Natl Acad Sci U S A. pii: 201812016. doi: 10.1073/pnas.1812016115.

Gaia Gestri, Naiara Bazin-Lopez, Clarissa Scholes and Stephen W. Wilson (2018)
Cell Behaviors during Closure of the Choroid Fissure in the Developing Eye.
Frontiers in Cellular Neuroscience. doi.org/10.3389/fncel.2018.00042

Anna M. Krasnow  1, Marc C. Ford  , Leonardo E. Valdivia, Stephen W. Wilson  and David Attwell (2018)
Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo
Nature Neuroscience. 2018 .doi:10.1038/s41593-017-0031-y

Stainier DYR, Raz E, Lawson ND, Ekker SC, Burdine RD, Eisen JS, Ingham PW, Schulte-Merker S, Yelon D, Weinstein BM, Mullins MC, Wilson SW, Ramakrishnan L, Amacher SL, Neuhauss SCF, Meng A, Mochizuki N, Panula P, Moens CB.(2017)
Guidelines for morpholino use in zebrafish.
Plos Genetics. 2017 Oct 19;13(10):e1007000. doi: 10.1371/journal.pgen.1007000.

Shainier, I., Buchshtab, A., Hawkins, T.A., Wilson, S.W., Cone, R.D., and Gothilf, Y. (2017)
Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish.
Sci Rep.  2017 Mar 20;7:44777. doi: 10.1038/srep44777.

Karin Tuschl, Esther Meyer, Leonardo E. Valdivia, Ningning Zhao, Chris Dadswell, Alaa Abdul-Sada, Christina Y. Hung, Michael A. Simpson, W. K. Chong, Thomas S. Jacques, Randy L. Woltjer, Simon Eaton, Allison Gregory, Lynn Sanford, Eleanna Kara, Henry Houlden, Stephan M. Cuno, Holger Prokisch, Lorella Valletta, Valeria Tiranti, Rasha Younis, Eamonn R. Maher, John Spencer, Ania Straatman-Iwanowska, Paul Gissen, Laila A. M. Selim, Guillem Pintos-Morell, Wifredo Coroleu-Lletget, Shekeeb S. Mohammad, Sangeetha Yoganathan, Russell C. Dale, Maya Thomas, Jason Rihel, Olaf A. Bodamer, Caroline A. Enns, Susan J. Hayflick, Peter T. Clayton, Philippa B. Mills, Manju A. Kurian & Stephen W. Wilson (2016)
Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia
Nat Commun. 2016 Jun 10

Turner, K. J., Hawkins, T. A., Yáñez, J., Anadón, R., Wilson, S. W., & Folgueira, M (2016)
Afferent Connectivity of the Zebrafish Habenulae
Front Neural Circuits. 2016 Apr 26;10:30. doi: 10.3389/fncir.2016.00030. eCollection 2016.

Gaston-Massuet C, McCabe MJ, Scagliotti V, Young RM, Carreno G, Gregory LC, Jayakody SA, Pozzi S, Gualtieri A, Basu B, Koniordou M, Wu CI, Bancalari RE, Rahikkala E, Veijola R, Lopponen T, Graziola F, Turton J, Signore M, Mousavy Gharavy SN, Charolidi N, Sokol SY, Andoniadou CL, Wilson SW, Merrill BJ, Dattani MT, Martinez-Barbera JP. (2016)
Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans. 
Proc Natl Acad Sci U S A. 2016 Jan 13. pii: 201503346.

 

 

WILSON LAB  / RESEARCH PROJECTS / IMAGES / PUBLICATIONS / PEOPLE / JOIN US
ZEBRAFISH UCL HOME

 
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Outreach


Outreach


outreach

We believe that science is meant to be shared, and not just with other scientists.

Below are a few details of some of the activities in which Zebrafish UCL labs participate in to disseminate science to the public.

A-Level Placements at Zebrafish UCL
The 2018 application deadline has now passed for Wilson/Rihel/Bianco/Tada Lab A-Level Work Experience Program for 2018. Click here for more information about the programme. 

 
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People


People


People

Past colleagues can be found here. 

 
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Join Us


Join Us


Join us

 

We encourage applications from prospective students and postdocs.

We are represented on the following PhD programs:

Wellcome Neuroscience, Wellcome Clinical PhD programme, LMCB programme in molecular cell biology, MRC and BBSRC DTPs, and many UCL Masters programmes including; MSc Neuroscience, MSc Genetics of Human Disease, MSc Biomedical Sciences and Biosciences MRes.

Please contact Steve Wilson (s.wilson@ucl.ac.uk) for more information. 

 

 

Funding

The Wilson lab currently receives funding from: